Lichen striatus (LS) occurs at any age, and presents most often (above 50% of cases) in children aged between 5 and 15 years. At first, small, pink, lichenoid, and discrete papules appear and coalesce rapidly, and then extend to form a dull red, slightly-scaly, linear band between 2 mm to 2 cm in width. The [...]

Continue reading " Lichen Striatus in a Girl: DISCUSSION "

A 15-year-old girl presented with a 2-month his­tory of an itchy eruption with a linear arrangement from the dorsolateral side of the left foot to the posterior aspect of the left thigh. She had no relevant medical history or laboratory tests. The lesion was a band-like, interrupted, slightly-erythe- matous plaque, which extended the entire length [...]

Continue reading " Lichen Striatus in a Girl: CASE REPORT "

INTRODUCTION Lichen striatus (LS) is an uncommon disorder that manifests as continuous or interrupted erythematous papules showing a unilateral pattern and linearity corresponding to Blaschko lines. LS mainly occur in children from 5 to 15 years of age. The eruption is usually asymptomatic and sponta­neously recovers within 3-6 months in most cases, but often leaves [...]

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Generalized granuloma annulare (GGA) is an uncommon variant of granuloma annulare (GA), representing 8% to 15% of all cases of GA. It is defined as affecting at least the trunk and either the upper, lower, or both, extremities . GGA most frequently occurs in middle-aged to elderly adults, between 30 and 60 years old. However, [...]

Continue reading " Two Cases of Generalized Granuloma Annulare in Infants: DISCUSSION "

Case 1 A 5-month-old male infant presented with a month-long history of gradually spreading erythema­tous papules on his trunk, upper and lower extremities. Skin examination revealed multiple, well-demarcated, erythematous, 1- to 5-mm-sized, and firm papules on his chest, abdomen, and both arms and legs (Fig. 1). Most of the papules were diffusely scattered. In the [...]

Continue reading " Two Cases of Generalized Granuloma Annulare in Infants: CASE REPORTS "

INTRODUCTION Granuloma annulare (GA) is a benign, granulo­matous skin disease of unknown cause. Generalized granuloma annulare (GGA) is an uncommon variant of GA, which is characterized by a widespread papular eruption and focal necrobiosis of collagen and granulomatous infiltration.

Continue reading " Two Cases of Generalized Granuloma Annulare in Infants "

Dean et al found increased expression of integrin a-1, a-2 subunits. This increased expression remai­ned when the fibroblasts were transferred to matrix. These results pointed to a primary defect of integrins or integrin regulators. Recently, Herrmann et al showed that mice with targeted disruption of the fatty acid transport protein 4 gene (Fatp4) show clear [...]

Continue reading " A Case of Restrictive Dermopathy: DISCUSSION continue "