Genotyping of the eNOS Polymorphism
DNA was extracted from the whole EDTA blood by means of a standard procedure (QIAmp Blood Kit, Qiagen). The variant of eNOS gene being analyzed is the G894T, in which a substitution of G to T at nucleotide position 894 results in a replacement of glutamic acid for aspartic acid at [...]

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Study Sample
The study consisted of self-reported African Americans selected from a larger population-based cohort of participants aged 18 years or older who were consecutively recruited from barbershops, shopping malls, churches, community organizations/centers and health fairs in the south and southwest metropolitan of Atlanta. Ninety healthy nor-motensive subjects (54 females and 36 males, mean age 44 [...]

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Blood pressure (BP) in the high-normal range is now considered a prehypertensive state/borderline hypertension, and its importance as a risk factor for the development of cardiovascular (CV) disease has been consistently demonstrated across various populations. Longitudinal data from the Framingham Heart Study have recently indicated that men and women with an initial high-normal BP had [...]

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