Case 1 A 5-month-old male infant presented with a month-long history of gradually spreading erythematous papules on his trunk, upper and lower extremities. Skin examination revealed multiple, well-demarcated, erythematous, 1- to 5-mm-sized, and firm papules on his chest, abdomen, and both arms and legs (Fig. 1). Most of the papules were diffusely scattered. In the [...]
Continue reading " Two Cases of Generalized Granuloma Annulare in Infants: CASE REPORTS "
INTRODUCTION Granuloma annulare (GA) is a benign, granulomatous skin disease of unknown cause. Generalized granuloma annulare (GGA) is an uncommon variant of GA, which is characterized by a widespread papular eruption and focal necrobiosis of collagen and granulomatous infiltration.
Continue reading " Two Cases of Generalized Granuloma Annulare in Infants "
Dean et al found increased expression of integrin a-1, a-2 subunits. This increased expression remained when the fibroblasts were transferred to matrix. These results pointed to a primary defect of integrins or integrin regulators. Recently, Herrmann et al showed that mice with targeted disruption of the fatty acid transport protein 4 gene (Fatp4) show clear [...]
Continue reading " A Case of Restrictive Dermopathy: DISCUSSION continue "
Restrictive dermopathy (RD) is a congenital diso-Collagen bundles are oriented parallel to the epidermis and elastic fibers are absent (A: H & E, x 200, B: Verhoeff-van Gieson, x 200). rder typified by an abnormal face, rigid skin and flexion contractures. This disorder was first described by Toriello in 1983, and Witt et al used [...]
Continue reading " A Case of Restrictive Dermopathy: DISCUSSION "
A female infant was born to a 31-year-old gravida 2, para 1, abortion 1 woman at a gestational age of 31 weeks. The pregnancy was complicated by polyhydramnios and a cesarean section was performed because of fetal distress. The infant weighed 1110я (<Ю percentile), the crown to heel measured 33 cm long (<10 percentile) and [...]
Continue reading " A Case of Restrictive Dermopathy: CASE REPORT "
INTRODUCTION Restrictive dermopathy (RD) is a rare, autosomal- recessive, lethal skin disease. It is characterized by rigid and tight adherent skin, multiple joint contractures, a typical facial appearance and pulmonary hypoplasia. Facial anomalies consist of micrognathia, low-set ears, a fixed open mouth, and small pinched nose. Because of restricted joint movement, the majority of patients [...]
Two of the test questions were designed to determine participants’ knowledge of the criteria for severe malaria, as patients who meet these criteria and those who are unable to tolerate oral therapy should be given IV therapy. Scores on these questions and feedback from participants indicated confusion about one of these questions, which presented 3 [...]
Continue reading " Evaluation of a Web-Based Malaria Education Module: DISCUSSION part 2 "
