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	<title>Canadian Medicine &#187; agents</title>
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		<title>Pharmacologic management of refractory depression</title>
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		<pubDate>Wed, 01 Oct 2008 16:25:04 +0000</pubDate>
		<dc:creator>Michel</dc:creator>
				<category><![CDATA[Depression]]></category>
		<category><![CDATA[agents]]></category>
		<category><![CDATA[antidepressants]]></category>
		<category><![CDATA[disorder]]></category>
		<category><![CDATA[Drugs]]></category>
		<category><![CDATA[Major depression]]></category>
		<category><![CDATA[medication]]></category>

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		<description><![CDATA[Major depression is a common and debilitating disorder that affects 10% to 15% of the population each year. Advances in understanding the psychopharmacology of depression has lead to the introduction of several new classes of antidepressant medication in the past decade. Despite these advances, however, patients&#8217; overall response to any given pharmacologic approach continues to [...]]]></description>
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