It has been known for some time that colesevelam (Wel-Chol, Sankyo), a bile acid-binding resin indicated for lowering low-density lipoprotein-cholesterol (LDL-C) levels, reduces glucose levels in individuals with type-2 diabetes. Given that a proportion of this population cannot use generic metformin (Glucophage canadian, Bristol-Myers Squibb) because of elevated cre-atinine values, and given that another group [...]

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Intensive Insulin Therapy To help patients meet their glycosylated hemoglobin (HbA1c) goals, more of them should be using basal-bolus, or “intensive,” insulin. With intensive insulin treatment, patients give themselves an injection of short-acting insulin before each meal and an injection of longer-acting insulin before going to bed.

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