We were unable to evidence any correlation be­tween viral shedding and CMV serology; this may be due to the lack of sensitivity or specificity of the complement-fixation test or to a lack of serologic response from critically ill patients. Conversely, we observed a significantly higher rate of viral infection in female patients. While it is [...]

Continue reading " Incidence and Morbidity of Cytomegaloviral Infection in Patients: DISCUSSION part 2 "

As early as 1968, blood transfusions used in cardiac surgery had been shown to be associated with risk of CMV infection, as evidenced by CMV serologic re­sponse; however, the incidence of reported CMV infection fluctuates between 40 percent in earlier studies and 1.5 to 12 percent in recent reports and, when considering only viremia, between [...]

Continue reading " Incidence and Morbidity of Cytomegaloviral Infection in Patients: DISCUSSION "

Morbidity Laboratory abnormalities are shown in Table 2. The incidence of atypical lymphocytosis was significantly increased in VE 4- patients, compared with VE — patients (55 percent [16/29] vs 30 percent [26/86], respectively; p<0.05), especially when considering a threshold above 200/cu mm (31 percent [9/29] vs 7 percent [6/86], respectively; p<0.01). Frank mono- nucleosis-like reaction [...]

Continue reading " Incidence and Morbidity of Cytomegaloviral Infection in Patients: RESULTS part 2 "

Incidence of CMV Excretion Clinical characteristics of the 115 patients are shown in Table 1. Viral shedding was found in 29 (25 percent) of 115 patients, with CMV isolated from the blood in 20, from urine in six, and from both sites in three patients. The age, type of surgery, delay between ECC and first [...]

Continue reading " Incidence and Morbidity of Cytomegaloviral Infection in Patients: RESULTS "

Fbtients From January 1981 to June 1986, some 136 consecutive adult patients were admitted to the ICU of Bichat Hospital, Paris, referred from seven Parisian surgical departments because of mediastinitis following cardiac surgery. Patients were included in the study when viral cultures could be performed within ten days after surgical dёbridement. Ten patients died before [...]

Continue reading " Incidence and Morbidity of Cytomegaloviral Infection in Patients: MATERIALS AND METHODS "

Infection with CMV following cardiac surgery was first recognized as a syndrome resembling infec­tious mononucleosis, and in most cases, documented infection with CMV in nonimmunosuppressed adults produces little, if any, disease; however, concomitant viral infection may increase susceptibility to and severity of sepsis in patients with bacterial infection. Immunologic disturbances with CMV infection have been [...]

Continue reading " Incidence and Morbidity of Cytomegaloviral Infection in Patients "

Study in an inner-city HIV (Viramune drug treating HIV infection) clinic in south central Los Angeles demonstrated that among those who attend the clinic, the prevalence of diabetes (Generic Glucophage is used to treat a type of diabetes mellitus) among patients on protease inhibitors is 12%. None of the patients who were not taking Pis developed diabetes. [...]

Continue reading " Prevalence and Incidence of Diabetes in HIV-infected: DISCUSSION "